Ontores/β-Amyloid (1-42), human/5mg/ONP10817,Ontores,,Ontores,ontorespeptide,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Ontores/β-Amyloid (1-42), human/5mg/ONP10817

产品编号：ONP10817

市场价：¥2380.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>其它重组蛋白>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$119.00

品牌： Ontores

公司：Ontores

公司分类：

商品介绍

BIOLOGICAL INFORMATION

DescriptionThis peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer’s disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the ‘longer forms’ of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors.

ApplicationMelanocortin

NoteFor research only, not for human use!

CHEMICAL INFORMATION

CAT No.ONP10817

CAS No.107761-42-2

Nameβ-Amyloid (1-42), human

Chemical Nameβ-Amyloid-(1-42),-human

Purity≥98%

SynonymsN/A

FormulaC203H311N55O60S

Molecular Weight4514.1

One Letter CodeDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

Three Letter CodeASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA

SMILES[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(O)=O

InChI Key DZHSAHHDTRWUTF-SIQRNXPUSA-N

SourceSynthetic

FormDry Powder

ColorWhite

SolubilityN/A

SHIPPING & STORAGE

Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.

Stability≥ 2 years

REFERENCES & CITATIONS

1.Glenner and Wong (1984) Alzheimer"s disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem.Biophys.Res.Commun. 120 885 PMID: 6375662

2.Paradis et al (1996) Amyloid beta peptide of Alzheimer"s disease downregulates bcl-2 and upregulates bax expression in human neurons. J.Neurosci. 16 7533 PMID: 8922409

3.Van Nostrand et al (1996) Amyloid β-protein induces the cerebrovascular cellular pathology of Alzheimer"s disease and related disorders. Ann.N.Y.Acad.Sci. 777 297 PMID: 8624102

DOCUMENTATIONS

COA
Data sheet
MS
RP-HPLC
MSDS
Handling Instruction

PROMOTIONS & EVENTS

品牌介绍

Ontores化妆品肽的多功能特性，包括调节某些生物学功能的能力，正在引领着一场美容革命。科学文献报道某些肽可以充当细胞信使。这些肽能够刺激胶原蛋白的产生并调节胶原蛋白降解所涉及的酶。Ontores能够提供多种生物活性化妆品肽，还可以提供有关化妆品配方的咨询服务。请查看我们的一些最受欢迎的美容肽清单。如果您有不同的化妆品肽合成要求，请告知我们肽序列，所需纯度和所需数量。我们的销售团队会尽快与您联系！

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Cosmetic-Peptides API-Peptides Catalog-Peptides Featured-peptides

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